Mary Shackleford
- Date of birth: Jan 20, 1752
- Place of birth: Prince William County, Virginia
- Date of death: After 1827
- Place of death: Prince William County, Virginia
- Father:
James Shackleford
- Mother: Elizabeth Scott
- Marriage:
George Grant Sr.
Mar 12, 1771 Fauquier County, Virginia
- Children:
- George GRANT , Jr.
- Mary GRANT
- Nancy GRANT
- James GRANT
- Judith GRANT
- Peggy B. GRANT
- Betsy GRANT